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Ezetimibe reduces cholesterol absorption and interrupts enterohepatic cholesterol recirculation. Bempedoic acid, a prodrug activated in the liver, lowers ldl and apob through hepatic-specific Abstract an elevated ldl-cholesterol is a potent risk factor for atherosclerotic cardiovascular disease (ascvd).
The cornerstone รขโฌยฆ Data are limited regarding the safety and efficacy of bempedoic acid treatment in long-term studies involving patients with hypercholesterolemia who are receiving guideline-recommended statin therapy. This information is provided to support primary care clinicians prescribing bempedoic acid and bempedoic acid with ezetimibe (nilemdoยฎ and nustendiยฎ) for treating primary รขโฌยฆ Key points bempedoic acid is a novel lipid-lowering therapy that inhibits adenosine triphosphate (atp)-citrate lyases and has been shown to decrease low-density lipoprotein cholesterol (ldl-c) by รขโฌยฆ Bempedoic acid is a new treatment for high cholesterol. It can be used when statins are not suitable and ezetimibe is not working well enough on its own.
Bempedoic acid is a new treatment for high cholesterol. It can be used when statins are not suitable and ezetimibe is not working well enough on its own.